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HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation. HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation

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NIAID Data Ecosystem2026-03-14 收录
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RNA-seq experiments were performed to assess effects of degradation of HDAC3 and HDAC8 on transcriptome Overall design: Cells were treated with control (DMSO), an HDACi (UF010), PROTACs (YX968, YX26862) that degrade HDAC3/HDAC8, or a negative control (YX968-NC) for various lengths of time

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2023-03-22
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