Pronounced and Extensive Microtubule Defects in a Saccharomyces cerevisiae DIS3 Mutant

The recently proposed exozyme hypothesis posits that subunits of the RNA processing exosome assemble into structurally distinct protein complexes that function in disparate cellular compartments and RNA metabolic pathways新近提出的外酶假说（exozyme hypothesis）指出，RNA加工外切酶体（RNA processing exosome）的亚基可组装形成结构迥异的蛋白质复合物，此类复合物在不同的细胞区室与RNA代谢通路中行使功能。