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Crystal structure of SARS-CoV-2 Mpro with compound C4

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Protein Data Bank Japan2026-03-04 更新2026-03-21 收录
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资源简介:
Crystal structure of SARS-CoV-2 Mpro with compound C4 Descriptor: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide Authors: Worrall, L.J, Lee, J, Strynadka, N.C.J. Deposit date: 2022-05-24 Release date: 2023-08-30 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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2022-05-24
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