Literature-based drug–drug similarity for drug repurposing: impact of Medical Subject Headings term refinement and hierarchical clustering - Supplementary Material

supplementary material

Section 1: Drug list curation procedure

Section 2: Reference Drug cluster preparation based on ATC drug classification

Section 3: Misclassification Counting

Section 4: Cluster-wise summary of results obtained from various K-means Clustering Experiments

Section 5: Cluster-wise summary of results obtained from various Hierarchical Clustering Experiments
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supplementary tables 
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  Supplementary Table1: Description of the Classes and Sub-classes from the MeSH hierarchy which were considered for creation of the refined MeSH terms

Supplementary Table 2. Description of drugs which have been previously suggested for repurposing and could also be predicted using results of various in silico experiments conducted using k-means clustering

Supplementary Table 3.  Description of drugs which have been previously suggested for repurposing and could also be predicted using results of various in silico experiments conducted using hierarchical clustering
 Supplementary Table 4. Repurposing suggestion details - Glyburide 

Supplementary Table 5.  Repurposing suggestion details - Stanozolol

Supplementary Table 6.  Repurposing suggestion details - Rimexolone

Supplementary Table 7.  Repurposing suggestion details - Carbachol

Supplementary Table 8.  Repurposing suggestion details - Pilocarpine

Supplementary Table 9.  Repurposing suggestion details - Aminophylline

Supplementary Table 10.  Repurposing suggestion details - Theophylline
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