Chlorosilane-Promoted Addition Reaction of Isocyanides to 3,4-Dihydroisoquinoline N‑Oxides
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The addition reaction of isocyanides to 3,4-dihydroisoquinoline N-oxides in the presence of TMSCl has been demonstrated, with the corresponding 1,2,3,4-tetrahydroisoquinoline-1-carboxylamides being obtained in moderate to high yields. A wide range of 3,4-dihydroisoquinoline N-oxides and isocyanides were applicable to this reaction.
创建时间:
2016-02-20



