Differences in brain metabolic activation to the task (percent change) when given with MP when compared with placebo (PL) between subjects in whom MP attenuated brain activation versus those in whom it enhanced activation along with their baseline metabolic measures.

Two subjects showed no differences between MP and placebo (data not included). Comparisons correspond to chi square for the subject numbers (Ss) and to student t-tests (unpaired, two test) for the other comparisons.