MIC of selected compounds against drug-resistant <i>Mtb</i> strains.

NIAID Data Ecosystem2026-05-02 收录

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https://figshare.com/articles/dataset/MIC_of_selected_compounds_against_drug-resistant_i_Mtb_i_strains_/29188038 数据链接链接失效反馈

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MIC of selected compounds against drug-resistant Mtb strains.

创建时间：

2025-05-29

Complete analysis of data from screening for antitubercular activity and physico chemical properties of the hit compounds.

抗结核药物

化合物活性分析

Rifampicin and Isoniazid were taken as controls. MIC values for controls against M. smegmatis are Rif-2.43±0.02μM and Inh-11.03±0.05 μM and H37Rv are Rif-0.08±0.01μM and Inh-0.22±0.3 μM.

NIAID Data Ecosystem60

A competitive activity-based protein profiling platform yields cell wall synthesis inhibitors active against replicating and non-replicating Mycobacterium tuberculosis

抗结核药物

细胞壁生物学

The identification and validation of a small molecule's targets is a major bottleneck in the discovery process for tuberculosis antibiotics. Activity-based protein profiling (ABPP) is an efficient too

NIAID Data Ecosystem40

Bacterial and fungal strains tested.

微生物耐药性测试

临床菌株分析

#methicillin-susceptible*multi-resistantBacterial and fungal strains tested.

Figshare2015-12-03 更新30

A novel biosafety level 2 compliant tuberculosis infection model using a Δ leuD Δ panCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella

结核病传播建模

抗结核药物

Mammalian infection models have contributed significantly to our understanding of the host-mycobacterial interaction, revealing potential mechanisms and targets for novel antimycobacterial therapeutic

NIAID Data Ecosystem50

Silica catalyzed one pot synthesis of hybrid thiazolidin-4-one derivatives as anti-tubercular and anti-inflammatory agent by attenuating COX-2 pathway

药物化学

抗结核药物

A novel series of a hybrid class of hybrid thiazolidin-4-one derivatives were designed and synthesized through one-pot catalytic synthesis. The reaction was catalyzed in the presence of silica-H 2

DataCite Commons2020-08-26 更新40

MIC of selected compounds against drug-resistant <i>Mtb</i> strains.

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