EGFR (T790M/V948R) in complex with quinazolinone allosteric inhibitor
收藏Protein Data Bank Japan2023-10-18 更新2026-04-25 收录
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https://pdbj.org/mine/summary/7ltx
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EGFR (T790M/V948R) in complex with quinazolinone allosteric inhibitor Descriptor: (2R)-2-{5-fluoro-6-[4-(1-methylpiperidin-4-yl)phenyl]-4-oxoquinazolin-3(4H)-yl}-2-phenyl-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ... Authors: Beyett, T.S, Eck, M.J. Deposit date: 2021-02-20 Release date: 2022-02-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC. Bioorg.Med.Chem.Lett., 68, 2022
创建时间：
2021-02-20
