Doxorubicin-treated Cardiomyocytes - Molecular Cartography 100 genes

We utilized a chemically defined protocol to differentiate human induced pluripotent stem cells (iPSCs) into beating cardiomyocytes and treated them with either DMSO (vehicle) or 2.5 μM DOX for twelve hours before fixation. Single molecule spatial transcriptomes were measured by Resolve Bioscience using Molecular Cartography for 100 genes important for cardiomyocyte health and function. <br> Replicates A1 and A2 correspond to vehicles while replicates B1 and B2 correspond to DOX treated samples.