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Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

NIAID Data Ecosystem2026-05-02 收录

生殖细胞发育

Wnt信号通路调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE288186 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-03-14

Wnt信号通路调控

胚胎发育转录组学

We report ChIP-Seq experiments to profile the genomic binding dynamics of ß-catenin, SOX17, SOX2 and TCF/LEF TFs in definitive endoderm and neuromesodermal progenitor cells and RNA-Seq/ATAC-Seq exper

NIAID Data Ecosystem90

10X Genonics Drop-seq single-cell RNA-seq of neonatal (P1.5) testis cells from mice treated with DMSO or Retinoic Acid.

单细胞转录组学

生殖细胞发育

To reveal distinct transcriptomes associated with response of neonatal prospermatogonia to retinoic acid (RA), unselected testis cells from animals treated with RA or DMSO were used for Drop-Seq analy

NIAID Data Ecosystem30

Effect of Morc1 knock out on gonocyte chromatin and transcriptome [RNA-Seq 2]

生殖细胞发育

表观遗传调控

To investigate the function of Morc1 to chromatin state during gonocyte stage when around 10,000 copies of transposons are deregulated. Overall design: We performed ATAC-seq, RNA-seq, ChIP-seq (for H3

NIAID Data Ecosystem10

Tdrd6a recruits Ziwi-bound piRNAs and coordinates deposition of germ plasm mRNAs into primordial germ cells [RIP-Seq]. Danio rerio

生殖细胞发育

piRNA调控

Germ plasm, the Balbiani body and nuage are evolutionary conserved structures essential for germ cell specification and maintenance. We describe Tdrd6a as a component of these structures with two dist

NIAID Data Ecosystem80

Data_Sheet_1_Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice.pdf

小鼠面部发育

Wnt信号通路调控

The R-spondin (RSPO) family of proteins potentiate canonical WNT/β-catenin signaling and may provide a mechanism to fine-tune the strength of canonical WNT signaling. Although several in vitro studies

NIAID Data Ecosystem20

Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

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