Directed Methylation with Long-read Sequecing (DiMeLo-seq)
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https://www.ncbi.nlm.nih.gov/sra/SRP332724
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资源简介：
DiMeLo-seq utilizes a protein A Hia5 fusion to direct adenine methylation at specific regions of the genome using antibodies for chromatin-bound factors. Adenine and cytosine methylation are then read out by methylation-sensitive long-read sequencing. This approach allows mapping of protein-DNA interactions through highly repetitive regions of the genome.
创建时间：
2022-04-06
