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Consequences of aneuploidy in human fibroblasts with trisomy 21

NIAID Data Ecosystem2026-03-12 收录

唐氏综合征转录组

非整倍体基因表达

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP271793 数据链接链接失效反馈

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资源简介：

RNA-Seq of primary human fibroblasts Overall design: Compare gene expression of trisomy fibroblasts to euploid controls

应用场景：

创建时间：

2020-10-26

非整倍体基因表达

植物基因组失衡效应

Aneuploidy has profound effects on an organism, typically more so than polyploidy, and the basis of this contrast is not fully understood. A dosage series of maize chromosome arm 1L was used to compar

NIAID Data Ecosystem90

Disomes and Disomes ubp6∆ vs. wild-type

酵母转录组学

非整倍体基因表达

Transcriptional profiling of anreuploid yeast strains grown in rich medium YEPD Cells were grown in YEPD at 30 degrees

NIAID Data Ecosystem90

Additional file 7 of The transcriptome profile of human trisomy 21 blood cells

唐氏综合征转录组

基因表达验证

Additional file 7: Supplementary Table 6. Primer pairs used for TRAM map experimental validation by Real-Time RT-PCR.

Figshare2021-05-01 更新50

Domains of genomewide gene expression dysregulation in Down syndrome [array]

唐氏综合征转录组

基因表达失调

Trisomy 21 (T21) is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in T21, and to eliminate the noise of the genomic variability, we studied th

NIAID Data Ecosystem90

RNA-sequencing analysis of cerebral cortex in Down syndrome and controls

唐氏综合征转录组

脑皮层基因差异表达

To determine the relationship between m6A modification and gene expression, we analyzed the RNA-Seq data of the same cortex tissues as MeRIP-Seq analyzed Overall design: Three of cortex tissues from D

NIAID Data Ecosystem60

Consequences of aneuploidy in human fibroblasts with trisomy 21

资源简介：

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