Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10
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https://pdbj.org/mine/summary/3e34
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Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10 Descriptor: 3-{2'-[{[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl}(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)sulfamoyl]biphenyl-3-yl}propanoic acid, FARNESYL DIPHOSPHATE, Protein farnesyltransferase subunit beta, ... Authors: Hast, M.A, Beese, L.S. Deposit date: 2008-08-06 Release date: 2009-03-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
创建时间：
2008-08-06
