Genome assemblies: Horizontal transfer of pOXA-48 from a hypervirulent Klebsiella pneumoniae ST23/KL57 to Serratia marcescens

Zenodo2023-04-14 更新2026-04-07 收录

细菌耐药性

医院感染分子流行病学

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https://zenodo.org/record/7828250 数据链接链接失效反馈

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资源简介：

Hypervirulent Klebsiella pneumonia isolates express a range of virulence factors, often encoded on virulence plasmids. Occasionally these hypervirulent lineages acquire antimicrobial resistance genes rendering them multidrug-resistant. We describe the nosocomial transmission of a hypervirulent K. pneumoniae ST23/KL57 isolate carrying an NDM-1 and OXA-48 beta-lactamase among COVID-19 patients in a Danish university hospital. Furthermore, we characterize the plasmid structure and describe a within-patient horizontal transfer of a plasmid carrying a blaOXA-48 gene from K. pneumoniae ST23/KL57 to a Serratia marcescens isolate.

提供机构：

Bacteria, parasites and fungi, Statens Serum Institut, Copenhagen, Denmark; Department of Thoracic Anaesthesiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark; Maria-Anna Misiakou; Department Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig, Germany; Department of Infectious diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark; Department of Clinical Microbiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

创建时间：

2023-04-14