Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)–C(sp3) Cross-Electrophile Coupling
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下载链接:
https://figshare.com/articles/dataset/Synthesis_of_-Vitepyrroloid_A_and_-Vitepyrroloid_B_by_Late-Stage_Ni-Catalyzed_C_sp2_C_sp3_Cross-Electrophile_Coupling/6396857
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资源简介:
A concise
and scalable five-step synthesis of vitepyrroloids A
and B, two cytotoxic labdane diterpenoid alkaloids from Vitex
trifolia, is reported. The presented approach features a
Ni-catalyzed cross-electrophile coupling between a (+)-sclareolide-derived
alkyl iodide and 3-bromo-2-cyanopyrrole.
创建时间:
2018-05-31



