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Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)–C(sp3) Cross-Electrophile Coupling

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NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Synthesis_of_-Vitepyrroloid_A_and_-Vitepyrroloid_B_by_Late-Stage_Ni-Catalyzed_C_sp2_C_sp3_Cross-Electrophile_Coupling/6396857
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资源简介:
A concise and scalable five-step synthesis of vitepyrroloids A and B, two cytotoxic labdane diterpenoid alkaloids from Vitex trifolia, is reported. The presented approach features a Ni-catalyzed cross-electrophile coupling between a (+)-sclareolide-derived alkyl iodide and 3-bromo-2-cyanopyrrole.
创建时间:
2018-05-31
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