Epithelial cell RNA-seq in aged skin

NIAID Data Ecosystem2026-03-10 收录

衰老转录组

毛囊干细胞

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP065218 数据链接链接失效反馈

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资源简介：

Transcriptional analysis of hair follicle stem cells and epidermal cells in young and aged skin. Overall design: Isolation of murine epithelial keratinocytes for RNA-seq analysis from young (2mo) and aged (24mo) animals

创建时间：

2017-09-17

DUSP6 inhibits the proliferation of hair follicle stem cells (HFSCs) in vitro

毛囊干细胞

动物毛发遗传学

RNA-seq has shown that the DUSP6 and MAPK signaling pathways are associated with the production of high-quality brush hair (type III hair) in Yangtze River Delta white goats. However, there are few re

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Embryonic attenuated Wnt/Ã-catenin signaling defines niche location and long-term stem cell fate in hair follicle

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Wnt/β-catenin信号通路

Long-term adult stem cells sustain tissue homeostasis and regeneration throughout the lifetime of an organism. They are thought to originate from embryonic progenitors that acquired long-term self-ren

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Ox40-Cre-mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia

毛囊干细胞

脱发分子机制

To identify the mechanisms of impaired hair regeneration in Brd4-deleted follicle stem cells, we FACS sorted HFSCs from Rag1-/-Ox40-Cre and Rag1-/-Brd4f/fOx40-Cre mice and performed RNA-seq analysis c

NIAID Data Ecosystem10

Deep sequencing of human fibroblastic cell line IMR90, either proliferating or senescent, expressing either empty vector or Parkin, with or without CCCP treatment

衰老转录组

线粒体自噬基因调控

Gene expression changes were compared in proliferating and senescent human IMR90 cells, with either empty vector, Parkin, or Parkin+CCCP. Method: RNA was extracted, in triplicate, then sequenced with

NIAID Data Ecosystem60

RNA-seq of Danio rerio and Mus musculus skin for three different age groups

衰老转录组

年龄相关基因表达

Background: Comparison of temporal gene expression profiles. The RNA-seq data comprises 3 age groups: 2, 15 and 30 months for mouse skin; 5, 24 and 42 months for zebrafish skin. Illumina 50bp single-s

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Epithelial cell RNA-seq in aged skin

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