MitoPark Transgenic Mouse Model Recapitulates Gastrointestinal Dysfunction and Gut-Microbiome Changes of Parkinson's Disease
收藏NIAID Data Ecosystem2026-04-25 收录
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资源简介：
The MitoPark mouse is a genetic model for Parkinson's disease (PD) that replicates the progressive development of the key symptoms. GI disturbances is an important non-motor symptom which in this model is yet to be explored extensively. This study characterizes GI motility, gut-microbiome dysbiosis, intestinal inflammation and metabolic profile using neurochemical, genomic and metabolomic approaches.
创建时间：
2019-10-12
