Renal ischemia is the most common cause of acute kidney injury (AKI) that might be exacerbate lupus activity through neutrophil extracellular traps (NETs) and apoptosis. Here, the renal ischemia reper
To investigate the molecular mechanisms of LN, we performed RNA sequencing on the kidneys of 8- and 17-week-old female MRL/lpr and C57BL/6 mice. Overall design: RNA sequencing was performed to assess
ObjectiveTo define shared and unique features of SLE nephritis in mouse models of proliferative and glomerulosclerotic renal disease.MethodsPerfused kidneys from NZB/W F1, NZW/BXSB and NZM2410 mice we