Adad1 gene expression
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA907786
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资源简介：
ADAD1 is a testis-specific RNA binding protein expressed in post-meiotic spermatids whose loss leads to severely defective sperm morphology and male infertility. Previous work has implicated ADAD1 in translation regulation however, the drivers of the Adad1 phenotype remain unclear. Detailed morphological analysis of Adad1 mutant sperm demonstrated defective DNA compaction and head shaping while RNA sequencing in Adad1 mutant testes revealed minimal transcriptome changes, suggesting ADAD1 acts downstream of transcription. This work defines the molecular role of ADAD1 in dictating post-meiotic germ cell differentiation.
创建时间：
2022-12-02
