Data from: Inversion Invasions: when the genetic basis of local adaptation is concentrated within inversions in the face of gene flow
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https://datadryad.org/dataset/doi:10.5061/dryad.mkkwh712q
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Across many species where inversions have been implicated in local
adaptation, genomes often evolve to contain multiple, large inversions
that arise early in divergence. Why this occurs has yet to be resolved. To
address this gap, we built forward-time simulations in which inversions
have flexible characteristics and can invade a metapopulation undergoing
spatially divergent selection for a highly polygenic trait. In our
simulations, inversions typically arose early in divergence, captured
standing genetic variation upon mutation, and then accumulated many
small-effect loci over time. Under special conditions, inversions could
also arise late in adaptation and capture locally adapted alleles.
Polygenic inversions behaved similarly to a single supergene of large
effect and were detectable by genome scans. Our results show that
characteristics of adaptive inversions found in empirical studies (e.g.,
multiple large, old inversions that are FST outliers, sometimes
overlapping with other inversions) are consistent with a highly polygenic
architecture, and inversions do not need to contain any large-effect genes
to play an important role in local adaptation. By combining a population
and quantitative genetic framework, our results give a deeper
understanding of the specific conditions needed for inversions to be
involved in adaptation when the genetic architecture is polygenic.
提供机构:
Dryad
创建时间:
2022-05-19



