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Longitudinal scRNA-seq analysis of primary microglia from mice treated with ATV:4D9 and controls

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NIAID Data Ecosystem2026-03-14 收录
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This study employs single-cell RNAseq (10X Genomics platform) to determine the transcriptional effects of ATV:4D9 treatment on primary mouse microglia in a longitudinal study. Single dose of 10 mg/kg ATV:4D9 or 10 mg/kg ATV:RSV (control) treatments in hTfR knock-in animals were sacrificed at day 1, day 7, day 14 and day 28 post-dose for ex vivo analysis.

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2023-02-22
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