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Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [ChIP-seq]

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141244
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The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD). ]analysis of SNCA promoter interact regions
创建时间:
2022-09-29
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