Outcomes of the correlation analyses between the bone turnover markers (ProCI and NTx) released by the samples with the volume (expressed in percentage) strained above different strain effective levels.

Reported are the strain thresholds for which the coefficient of determination R2 was maximum (only when the p-value associated with the Spearman correlation analyses was significant). ‘Direction’ indicates whether the bone markers were increasing (↑) or decreasing (↓) with increasing the strained bone volume.a, p