This workbook contains three spreadsheets that summarize the predicted effects of single-nucleotide variants ascertained in the Nachman strains.

The first sheet (“SNPs”) summarizes the number of variants of different predicted functional classes in the Nachman strains. Numbers are presented for all variants in the Nachman strains and the subset of variants that are private to the Nachman strains and not observed in classical inbred strains included in the Mouse Genomes Project. The second spreadsheet (“HIGH Nachman Private”) lists SNPs private to the Nachman strains (i.e., not present in Mouse Genomes Project data) with HIGH predicted functional impact. Impacted genes, their associated Gene Ontology terms, and strains carrying the predicted deleterious allele are also included. The third spreadsheet (“GO Analysis”) presents the output of a GO enrichment analysis on genes in the “HIGH Nachman Private” spreadsheet against all genes in the M. musculus genome. (XLSX)