Role of the histone methylase G9a in pancreatic carcinogenesis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE149093
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资源简介：
Accumulating evidences propose the importance of epigenetic regulation in pancreatic carcinogenesis, but the mechanistic insights of a variety of histone modification process still remains to be elucidated. G9a functions as a transcriptional repressor via the methylating activity specific for histone H3 lysine9. We identified G9a as a critical factor in the development of murine pancreatic oncogenesis. Comparison of gene expression in P48-Cre; KrasG12D and P48-Cre; KrasG12D; G9a flox/flox Pancreas
创建时间：
2020-11-03
