Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13120
收藏Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13120 Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Isoform 4 of Bromodomain-containing protein 2, ... Authors: Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y. Deposit date: 2022-01-17 Release date: 2022-08-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors. J.Med.Chem., 65, 2022
创建时间：
2022-01-17
