Crystal structure of Schistosoma mansoni HDAC8 in complex with a tricyclic thieno[3,2-b]indole capped hydroxamate-based inhibitor, chlorine derivative
收藏Protein Data Bank Japan2024-01-31 更新2026-03-28 收录
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Crystal structure of Schistosoma mansoni HDAC8 in complex with a tricyclic thieno[3,2-b]indole capped hydroxamate-based inhibitor, chlorine derivative Descriptor: 5-[[(2R)-7-fluoranyl-2-phenyl-2,3-dihydrothieno[3,2-b]indol-4-yl]methyl]-N-oxidanyl-thiophene-2-carboxamide, Histone deacetylase 8, POTASSIUM ION, ... Authors: Saccoccia, F, Gemma, S, Campiani, G, Ruberti, G. Deposit date: 2021-07-06 Release date: 2022-07-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors. J.Biol.Chem., 298, 2022
创建时间：
2021-07-06
