The resistance of cancer cells to therapy is responsible for the death of most cancer patients. Epithelial-to-mesenchymal transition (EMT) has been associated with resistance to therapy in different c
A) Representative dose-effect curve plots of HCC827 and HCC4006 parental cell lines to the indicated TKIs. Cell viability was determined by MTT assays. The results are expressed as the percentage of c
Analysis of gene expression profiles of patient-derived colorectal cancer cell which is mono-cultured or co-cultured with CAFs in the presence of vehicle, JQ1, pacritinib or combo. Overall design: Ill