Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a bicyclic pyrazole inhibitor RK-73134
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a bicyclic pyrazole inhibitor RK-73134 Descriptor: 1,2-ETHANEDIOL, Activin receptor type-1, SULFATE ION, ... Authors: Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. Deposit date: 2020-05-12 Release date: 2021-03-03 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva. Bioorg.Med.Chem.Lett., 38, 2021
创建时间：
2020-05-12
