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Rhodium(III)-Catalyzed Intermolecular Direct Amidation of Aldehyde C–H Bonds with <i>N</i>‑Chloroamines at Room Temperature

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NIAID Data Ecosystem2026-03-07 收录
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A Rh(III)-catalyzed direct aldehyde C–H amidation from aldehydes and N-chloroamines, prepared in situ from amines, has been developed via C–H bond activation under very mild reaction conditions. A variety of primary and secondary amines were used to afford the corresponding amides in moderate to excellent yields.

创建时间:
2016-02-19
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