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CCDB, A TOPOISOMERASE POISON FROM E. COLI
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2024-04-03
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Clostridium perfringens type A causes gas gangrene, which involves muscle infection. Both alpha toxin (PLC), encoded by the plc gene, and perfringolysin O (PFO), encoded by the pfoA gene, are importan
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Escherichia coli alpha-hemolysin HlyA induces host cell polarity changes, epithelial barrier dysfunction and cell detachment in human colon carcinoma Caco-2 cell model via PTEN-dependent dysregulation of cell junctions. Escherichia coli alpha-hemolysin HlyA induces host cell polarity changes, epithelial barrier dysfunction and cell detachment in human colon carcinoma Caco-2 cell model via PTEN-dependent dysregulation of cell junctions
Escherichia coli of the B2 phylotype reside in human and animal intestines. We addressed the questions which host cell processes were dysregulated by E. coli HlyA that can potentiate intestinal diseas
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CDTb Double Heptamer Long Form Mask 3 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry
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A Chloro-Bridged Heterobimetallic (η6‑Arene)ruthenium–Organotin Complex as an Efficient Topoisomerase Iα Inhibitor
The chloro-bridged heterobimetallic complex (η6-hexamethylbenzene)Ru(dmp)(μ-Cl)2Sn(CH3)2Cl2 was designed, synthesized, and characterized by various spectroscopic methods, viz. IR, 1H and 13C NMR,
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Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate
Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate
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