Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 1 mM Mg2+ for 1800s

NIAID Data Ecosystem2026-05-02 收录

跨损伤合成

DNA聚合酶动力学

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Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 1 mM Mg2+ for 1800s

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2025-06-04

DNA polymerase stalling at structured DNA predicts the stability of short tandem repeats

短串联重复序列

DNA聚合酶动力学

Short tandem repeats (STRs) significantly contribute to de novo mutagenesis, driving phenotypic diversity and genetic disease. Although highly diverse, their low complexity and repetitive nature induc

NIAID Data Ecosystem60

Conformational Transition Pathway of Polymerase β/DNA upon Binding Correct Incoming Substrate

DNA聚合酶动力学

DNA修复

The closing conformational transition of wild-type polymerase β bound to DNA template/primer before the chemical step (nucleotidyl transfer reaction) is simulated using the stochastic difference equat

NIAID Data Ecosystem40

Structure of C-terminal domain of human polymerase Rev1 in complex with PolD3 RIR-motif

DNA损伤修复

跨损伤合成

Structure of C-terminal domain of human polymerase Rev1 in complex with PolD3 RIR-motif Descriptor: DNA polymerase delta subunit 3, DNA repair protein REV1 Authors: Pustovalova, Y, Korzhnev, D. Deposi

Protein Data Bank Japan2024-05-01 更新20

Crystal structure of human polymerase eta complexed with Xanthine containing DNA

DNA损伤修复

跨损伤合成

Crystal structure of human polymerase eta complexed with Xanthine containing DNA Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP

Protein Data Bank Japan2023-10-18 更新40

Replication Pauses of the Wild-Type and Mutant Mitochondrial DNA Polymerase Gamma: A Simulation Study

DNA聚合酶动力学

线粒体遗传病

The activity of polymerase γ is complicated, involving both correct and incorrect DNA polymerization events, exonuclease activity, and the disassociation of the polymerase:DNA complex. Pausing of pol-

NIAID Data Ecosystem20

Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 1 mM Mg2+ for 1800s

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