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Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [microarray]. Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [microarray]

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA490187
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资源简介:
our study establishes FOXA1 as an important regulator of lineage plasticity mediated in part by TGF-β signaling and supports a novel therapeutic strategy to control lineage switching and potentially extend clinical response to antiandrogen therapies. Overall design: Microarray analysis on LNRII cells with control and TGFB3. Microarray analysis on LNCaP cells with control and FOXA1 knockdown followed by LY2157299 treatment
创建时间:
2018-09-10
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