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Trypanosoma brucei dihydrofolate reductase (TbDHFR) in complex with WR99210

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Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Trypanosoma brucei dihydrofolate reductase (TbDHFR) in complex with WR99210 Descriptor: 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Vanichtanankul, J, Yuvaniyama, J, Yuthavong, Y. Deposit date: 2011-04-08 Release date: 2011-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Trypanosomal dihydrofolate reductase reveals natural antifolate resistance Acs Chem.Biol., 6, 2011

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2011-04-08
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