crystal structure of furanopyrimidine 1 bound to lck
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crystal structure of furanopyrimidine 1 bound to lck Descriptor: 5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE, Proto-oncogene tyrosine-protein kinase LCK Authors: Martin, M.W. Deposit date: 2007-01-02 Release date: 2007-02-27 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties. Bioorg.Med.Chem.Lett., 17, 2007
创建时间:
2007-01-02



