Differences between the CPS gene clusters of strains KKBO-4 (cpsBO-4, 26,587 bp) or KK207-2 (cps207-2, 23,994 bp) and closely related CPS gene clusters detected in other sequenced genomes.

The dash indicates 100% identity. The cut-off values used for the inclusion in the analysis were ≥99% nucleotide identity and ≥99% of query coverage, based on results from a BLAST search performed at the NCBI website (http://blast.ncbi.nlm.nih.gov/) using either nr or wgs databases, using default values but without the low complexity filter option.aKPNIH21 was chosen as a representative of the outbreak clone described in reference 24.bstrains ST258 K26BO and ST258 K28BO, both described in reference 26, were characterized by identical CPS gene clusters.cstrains UHKPC02 and UHKPC06 were representatives of those included in the Klebsiella pneumoniae Genome Sequencing Center Project (http://gsc.jcvi.org/projects/gsc/klebsiella_pneumoniae/index.php).d2 out of 5 SNVs are located in intergenic regions.