Crystal structure of Peroxiredoxin I in complex with compound 19-064

Crystal structure of Peroxiredoxin I in complex with compound 19-064 Descriptor: Peroxiredoxin-1, methyl 3-[[(2~{R},4~{a}~{S},6~{a}~{R},6~{a}~{S},14~{a}~{S},14~{b}~{R})-2,4~{a},6~{a},6~{a},9,14~{a}-hexamethyl-10-oxidanyl-11-oxidanylidene-1,3,4,5,6,13,14,14~{b}-octahydropicen-2-yl]carbamoylamino]oxetane-3-carboxylate Authors: Zhang, H, Luo, C. Deposit date: 2023-11-22 Release date: 2024-06-19 Last modified: 2025-12-03 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Discovery of Urea Derivatives of Celastrol as Selective Peroxiredoxin 1 Inhibitors against Colorectal Cancer Cells J.Med.Chem., 67, 2024