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Crystal Structure of BRD4(1) bound to inhibitor BUX2 (9)

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal Structure of BRD4(1) bound to inhibitor BUX2 (9) Descriptor: (R,R)-2,3-BUTANEDIOL, Bromodomain-containing protein 4, ~{N}-[5-(azepan-1-ylsulfonyl)-2-methoxy-phenyl]-3-methyl-4-oxidanylidene-5,6,7,8-tetrahydro-2~{H}-cyclohepta[c]pyrrole-1-carboxamide Authors: Huegle, M. Deposit date: 2019-07-03 Release date: 2020-12-09 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: 4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines. J.Med.Chem., 63, 2020

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2019-07-03
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