Vitamin B12 partially rescues embryonic cell migration defects in C. elegans ephrin mutants by improving both propionic acid breakdown and one-carbon cycle metabolic pathways

Cell data files containing nuclei position data for all nuclei detected during embryonic development of <i>C. elegans</i> embryos. In this dataset all embryos are homozygous for the <i>vab-1(e2027)</i> mutation. Embryos were maintained on normal growth media (NGM) with OP50 <i>E. coli</i> or supplemented with 64 nM vitamin B12 (ado-cobalamin). Embryos either hatched or arrested as noted. Embryos carried a transgene driving expression of fluorescent histone protein to identify nuclei position using time-lapse confocal imaging. Images were collected every 1.5 minutes and data was analyzed with StarryNite and manually curated to the 350 cell stage. At this stage and prior, each nucleus represents and individual cell, which is named according to Sulston, 1983.