IL6R haplotype frequencies in cases and controls and risk of MI in SHEEP and of CHD in the PROCARDIS and IMPROVE studies associated with IL6R haplotypes.

Only diplotypes and haplotypes with a frequency>1% are reported in the table. The most common diplotype in block 1 and the most common haplotype in block 2 are taken as reference categories.Data from only three tag SNPs were available in the IMPROVE study (rs7553796 C/A (pairwise LD with rs4553185T/C, r2 = 0.96) rs8192284A/C and rs4072391T/C (pairwise LD with rs7514452T/C r2 = 0.98). Haplotype-21–1 represents both 12111 and 12121.IL6R haplotype frequencies in cases and controls and risk of MI in SHEEP and of CHD in the PROCARDIS and IMPROVE studies associated with IL6R haplotypes.