Efficient Synthesis of C–N-Coupled Heterobiaryls by Sequential N–H Functionalization Reactions
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https://figshare.com/articles/dataset/Efficient_Synthesis_of_C_N_Coupled_Heterobiaryls_by_Sequential_N_H_Functionalization_Reactions/2175919
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C–N-coupled heterobiaryls were synthesized by sequential N–H functionalization reactions: stereoselective rhodium-catalyzed N–H insertion, followed by regioselective palladium-catalyzed C–H amination. Because of the good substrate scope and excellent selectivity, the developed method presents a novel approach for the synthesis of heterobiaryls, which are potent antibiotics.
创建时间:
2016-02-13



