Neiburga2022 - Arabidopsis thaliana MEP pathway with isoprene synthesis

Kinetic model of extended MEP pathway in Arabidopsis thaliana for isoprene. This model was used for determining total optimization potential (TOP) of isoprene production in Arabidopsis thaliana using Spacescanner (https://github.com/atiselsts/spacescanner). This model was used to make designs D, E and F. An optimization task in COPASI can be perfomed using this model by accesing COPASI/Tasks/Optimization. Parameters which will be changed during the optimization and the optimization constraints can be selected. More description in Total optimization potential (TOP) approach based constrained design of isoprene and cis-abienol production in A. thaliana, Authors: Katrina D. Neiburga, Reinis Muiznieks, Darta M. Zake, Agris Pentjuss, Vitalijs Komasilovs, Johann Rohwer, Alain Tissier, Egils Stalidzans