Crystal structure of S. aureus FabI inhibited by SKTS1 Descriptor: 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADP NICOTINAMIDE-ADENINE-DINU

Protein Data Bank Japan2024-01-24 更新30

Turning Defense into Offense: Defensin Mimetics as Novel Antibiotics Targeting Lipid II

抗菌药物发现

细菌细胞壁靶向治疗

We have previously reported on the functional interaction of Lipid II with human alpha-defensins, a class of antimicrobial peptides. Lipid II is an essential precursor for bacterial cell wall biosynth

Figshare2016-01-18 更新20

Novel bacterial methionine aminopeptidase inhibitors

抗菌药物发现

细菌酶抑制

Novel bacterial methionine aminopeptidase inhibitors

NIAID Data Ecosystem40

Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases

抗菌药物发现

β-内酰胺酶抑制剂

Gram-negative pathogens expressing serine β-lactamases (SBLs) and metallo-β-lactamases (MBLs), especially those with carbapenemase activity, threaten the clinical utility of almost all β-lactam antibi

NIAID Data Ecosystem20