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Effects of Hnf4a deletion in the nephron lineage during kidney development

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NIAID Data Ecosystem2026-04-25 收录
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The goal of our study is to determine if Hnf4a is required for the formation of proximal tubules during kidney development. Overall design: Method: Hnf4a floxed allele was deleted in the nephron lineage using Six2GFPcre. Mouse embryonic kidneys at E18.5 were collected and subjected to RNA-seq analysis Examination of 4 groups; two controls (Hnf4a c/+ ; Six2GFPcre) and two mutants (Hnf4a c/c ; Six2GFPcre)

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2019-09-24
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