Series of 56 paired presentation, relapse and control samples from newly diagnosed, uniformly treated myeloma patients. Deep of treatment response and maintenance allocation (active observation or len

NIAID Data Ecosystem30

Comprehensive bioinformatics analysis reveals the hub genes and pathways associated with multiple myeloma

多发性骨髓瘤遗传学

生物标志物发现

While the prognosis of multiple myeloma (MM) has significantly improved over the last decade because of new treatment options, it remains incurable. Aetiological explanations and biological targets ba

Taylor & Francis Group2024-02-19 更新50

Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk

多发性骨髓瘤遗传学

蛋白质与染色质修饰与DNA修复

The high-risk pedigree (HRP) design is an established strategy to discover rare, highly-penetrant, Mendelian-like causal variants. Its success, however, in complex traits has been modest, largely due

NIAID Data Ecosystem40

ArrayCGH profiling of two B-cell lineage subpopulations in multiple myeloma

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