官方服务:
资源简介:
Aging-induced CD4+ T cell DNA sensing through KU complex potentiates autoimmunity
应用场景:
创建时间:
2021-01-25
相关数据集
Genetically-driven target tissue over-expression of CD40: A novel mechanism in autoimmune disease
The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid derived cells, many of which are targets for tissue specific autoimmune diseases, including d thyroi
NIAID Data Ecosystem50
CD4 + T cell proliferation following incubation of PBMCs ex vivo with different antigens.
CD4+ T cell proliferation following incubation of PBMCs ex vivo with different antigens.
NIAID Data Ecosystem40
Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery. Pogorelyy et al.
Supplementary spreadsheets for Pogorelyy et al, Cell. Rep. Med 2022 Supplementary Table 1: Differentially expressed genes for each functional Seurat cluster. Related to Fig. 1B. Supplementary Table 2
NIAID Data Ecosystem30
TLR signaling in C57BL/6J TLR7-tolerant CD3+ T-cells over the unmanipulated state.
Murine CD3+ T-cells were immunomagnetically purified from the spleens of C57BL/6J mice and were pretreated in vitro for three days in the presence of R848 (5 μg/ml). Unmanipulated T-cells served as ne
NIAID Data Ecosystem50
Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host.
The epitope sequence was cited in Nayak et al. Viral Immunol. 2010 Apr;23(2):169-80 [PMID:20373997]. Similar results were seen for (B10 x B10.S) F1 mice (H-2bxs). Also, little apparent difference was
ImmuneData30



