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Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism

NIAID Data Ecosystem2026-05-01 收录

免疫代谢

调节性T细胞

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235421 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-03-25

转录组学分析

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GSEA core enrichment - Oxphos - IL-10 immunodepleted vs low LPS plasma. (XLS 61 kb)

NIAID Data Ecosystem70

D- 2-hydroxyglutarate is an immunometabolite that accumulates in macrophages after TLR activation and inhibits inflammatory responses

免疫代谢

巨噬细胞炎症抑制

Macrophages undergo extensive metabolic rewiring upon activation and this serves many roles beyond the production of energy and anabolic building blocks. So-called immunometabolites that accumulate up

NIAID Data Ecosystem30

Genes in yeast two-hybrid screening.

宿主-病原体相互作用

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Intracellular bacterial pathogens exhibit heterogeneous replication rates within host macrophages, but the mechanisms by which they manipulate host factors for survival remain incompletely understood.

NIAID Data Ecosystem10

Pro-survival Lipid Sphingosine-1-Phosphate Metabolically Reprograms T cell to Limit its Anti-Tumor Activity

免疫代谢

T细胞功能调控

Sphingosine 1-phosphate (S1P), a pro-tumor survival bioactive lysophospholipid, generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via transducing S1P receptor 1 (

NIAID Data Ecosystem50

DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

免疫代谢

PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

NIAID Data Ecosystem30

Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism

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