Amyloid beta (Aβ) accumulates within neurons in the brains of early stage Alzheimer's disease (AD) patients. However, the mechanism underlying its potential toxicity remains unclear. To elucidate this
(1) Human data from [38] temporal from fovea (2) Mouse data from C57BL/6J; dorsal from optical axis Mean rod and cone densities in different regions of the human macula and the central mouse retina.
Cell types in the human retina are highly heterogeneous with their abundance varies by several orders of magnitude. To decipher the complexity of gene expression and regulation of the human retinal ce