Changes after treatment initiation with levothyroxine (group 2) or levothyroxine and progestogens or GH (group 3).

Dichotomous response options (‘yes‘ or ‘no‘) were provided to assess the improvement of hair and skin condition, growth, fitness and side effects. Comparison between groups was performed by using Wilcoxon-rank-sum test or t-test for numerical data and Chi-square two sample test for categorical data.