Developing the gene expression of glomerulus in anti-Thy1 nephritis. Rattus

we followed the course of anti-Thy1 nephritis from days 1 to 5, establishing gene expression profiles at each timepoint using microarrays to explore the development of immunity. Overall design: We established anti-Thy1 model by injection of anti-Thy1 antibody. The models were killed from day 1 to 5. The normal control group was killed at day 0. Three glomeruli of each of six rats per timepoint were subjected to microarray analysis.